The casual level of meibomian lipids in humans

Autor: John M. Tiffany, C. Jansweijer, Anthony J. Bron, C. K. S. Chew, P. G. Hykin, Shabtay Dikstein
Rok vydání: 1993
Předmět:
Zdroj: Current Eye Research. 12:255-259
ISSN: 1460-2202
0271-3683
DOI: 10.3109/02713689308999471
Popis: Using a modified skin surface lipid measuring instrument, the Meibometer, the amounts of meibomian lipid on the lid margins (the casual levels) of 421 subjects aged 1 to 94 years were measured. The lowest levels were found in children younger than 14 years (means +/- S.E.: males = 1.48 +/- 0.17, females = 1.53 +/- 0.17 micrograms lipid/mm2 lid margin surface) and rose with age, the highest levels being found in males aged 60-69 years (mean +/- S.E. = 3.26 +/- 0.18 micrograms lipid/mm2 lid margin surface). Male levels were higher than females in the 20-29 years age group but male and female levels became indistinguishable above the age of 50. These age- and sex-related changes differed markedly from those seen in skin surface lipid levels. The age-related changes in the casual levels of lid lipids remain unexplained although an endocrinological mechanism modified by morphological factors is considered.
Databáze: OpenAIRE