Hepatic sarcoidosis
| Autor: | Maria Karavalaki, Alexandras Karagiannidis, Anastasios Koulaouzidis |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Pathology
medicine.medical_specialty Cirrhosis Tuberculosis Sarcoidosis hepatic sarcoidosis medicine.medical_treatment Cholangitis Sclerosing Specialties of internal medicine Cholestasis Intrahepatic Liver transplantation Budd-Chiari Syndrome Asymptomatic Hepatitis Diagnosis Differential Cholestasis medicine Humans Liver granuloma Granuloma Hepatology medicine.diagnostic_test business.industry Liver Diseases liver sarcoid General Medicine medicine.disease RC581-951 idiopathic granulomatous hepatitis Portal hypertension medicine.symptom Liver function tests business cholestasis |
| Zdroj: | Annals of Hepatology, Vol 5, Iss 4, Pp 251-256 (2006) |
| ISSN: | 1665-2681 |
| Popis: | Sarcoidosis is a multisystem disease of unknown aetiology. Histological evidence of non-caseating granulomas represents the main finding. It affects mostly young people, targeting primary the lung and hilar lymph nodes although liver involvement is often encountered. Hepatic sarcoidosis covers a broad spectrum from asymptomatic hepatic granulomas formation and slightly deranged liver function tests to clinically evident disease with cholestasis or, in advanced cases, cirrhosis and portal hypertension. Other granulomatous diseases (mainly systemic infections like tuberculosis) should be excluded prior to treatment, as longstanding corticosteroid administration is the main stem of therapy. In advanced cases, liver transplantation represents the ultimate therapeutic option. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|