Antibiotic resistance in Escherichia coli isolates from poultry environment and UTI patients in Kerala, India: A comparison study
| Autor: | Stelvin Sebastian, Antriya Annie Tom, Joyal Anna Babu, Merin Joshy |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Veterinary medicine
040301 veterinary sciences medicine.drug_class 030231 tropical medicine Immunology Antibiotics India Microbial Sensitivity Tests Biology Microbiology Meropenem Poultry 0403 veterinary science 03 medical and health sciences 0302 clinical medicine Antibiotic resistance Ampicillin Drug Resistance Bacterial Escherichia coli medicine Animals Humans Immunology and Allergy Escherichia coli Infections General Veterinary business.industry 04 agricultural and veterinary sciences General Medicine biochemical phenomena metabolism and nutrition Amoxicillin Poultry farming bacterial infections and mycoses Antimicrobial Anti-Bacterial Agents Infectious Diseases Amikacin business medicine.drug |
| Zdroj: | Comparative Immunology, Microbiology and Infectious Diseases. 75:101614 |
| ISSN: | 0147-9571 |
| DOI: | 10.1016/j.cimid.2021.101614 |
| Popis: | There are only narrow insights regarding the antimicrobial resistance of pathogens in poultry environment in India and its transmission to humans. The use of antimicrobials in food animal production is not properly regulated in India. So, many clinically important antimicrobials are used indiscriminately.Our aim was to do a comparative analysis of antibiotic resistance in Escherichia coli isolates from poultry environment and UTI patients.Two poultry farms each from six areas in Muvattupuzha region of the state of Kerala in India were selected for the study. From each farm, samples of fresh fecal matter, litter from inside the shed, litter from outside the shed, nearby agricultural soil and control soilwere collected. E. coli was isolated from each sample, and antimicrobial susceptibility testing of E. coli was done with fifteen antibiotics. Antibiograms of UTI patients were collected from the tertiary care hospital included in the study and those were compared with the antibiograms of poultrysamples.All samples were resistant to ampicillin, amoxicillin, meropenem and tetracycline. Similar resistance pattern in poultry environment and UTI patients was seen for antibiotics such as ampicillin, amoxicillin, amikacin, and ofloxacin. A statistically significant difference (p.00601) was established in the total number of isolates resistant to various antibiotics from areas near to farms compared to those away from farms.E. coli were resistant not only to extended spectrum beta lactams but also to carbapenems which might have disseminated to environment where litter was used as manure. This might be due to irrational use of antibiotics in chicken and poultry feed as growth promoter. |
| Databáze: | OpenAIRE |
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