Asynchronous, out-of-sequence, transcontinental chain kidney transplantation: a novel concept
| Autor: | Stephan Busque, Marc L. Melcher, Garet Hil, Alan H. Wilkinson, Suzanne McGuire, S. Katznelson, Sandip Kapur, David Serur, Michael Charlton, Peter G. Schulam, Hans Albin Gritsch, Gabriel M. Danovitch, J. J. Del Pizzo, Jeffrey L. Veale, F. K. Butt |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Tissue and Organ Procurement ABO Blood-Group System medicine Living Donors Immunology and Allergy Humans Transplantation Homologous Pharmacology (medical) Organ donation Donor shortage Intensive care medicine Donor pool Kidney transplantation Transplantation business.industry Middle Aged medicine.disease Altruism Kidney Transplantation United States Asynchronous communication Donation Blood Group Incompatibility Creatinine Quality of Life Female business Donor kidney |
| Zdroj: | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 9(9) |
| ISSN: | 1600-6143 |
| Popis: | The organ donor shortage has been the most important hindrance in getting listed patients transplanted. Living kidney donors who are incompatible with their intended recipients are an untapped resource for expanding the donor pool through participation in transplant exchanges. Chain transplantation takes this concept further, with the potential to benefit even more recipients. We describe the first asynchronous, out of sequence transplant chain that was initiated by transcontinental shipment of an altruistic donor kidney 1 week after that recipient's incompatible donor had already donated his kidney to the next recipient in the chain. The altruistic donor kidney was transported from New York to Los Angeles and functioned immediately after transplantation. Our modified-sequence asynchronous transplant chain (MATCH) enabled eight recipients, at four different institutions, to benefit from the generosity of one altruistic donor and warrants further exploration as a promising step toward addressing the organ donor shortage. |
| Databáze: | OpenAIRE |
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