Mortality of Myocardial Infarction by Sex, Age, and Obstructive Coronary Artery Disease Status in the ACTION Registry–GWTG (Acute Coronary Treatment and Intervention Outcomes Network Registry–Get With the Guidelines)
| Autor: | Anne S. Hellkamp, Matthew T. Roe, Harmony R. Reynolds, Martha Gulati, Asha M. Mahajan, Karen Chiswell, Nathaniel R. Smilowitz |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Acute coronary syndrome Time Factors medicine.medical_treatment 030204 cardiovascular system & hematology Coronary Angiography Revascularization Coronary artery disease 03 medical and health sciences Percutaneous Coronary Intervention Sex Factors 0302 clinical medicine Risk Factors Clinical history Cause of Death Internal medicine Intervention (counseling) medicine Humans Hospital Mortality Registries 030212 general & internal medicine Myocardial infarction Acute Coronary Syndrome Non-ST Elevated Myocardial Infarction Aged Aged 80 and over business.industry Age Factors Coronary Stenosis Middle Aged medicine.disease United States Coronary arteries Treatment Outcome medicine.anatomical_structure Practice Guidelines as Topic ST Elevation Myocardial Infarction Female Guideline Adherence Cardiology and Cardiovascular Medicine business Lower mortality |
| Zdroj: | Circulation: Cardiovascular Quality and Outcomes. 10 |
| ISSN: | 1941-7705 1941-7713 |
| DOI: | 10.1161/circoutcomes.116.003443 |
| Popis: | Background— Sex differences in early mortality after myocardial infarction (MI) vary by age. MI with nonobstructive coronary arteries (MINOCA [ Methods and Results— Adults who underwent coronary angiography for acute ST-segment–elevation and non–ST-segment–elevation MI in the National Cardiovascular Data Registry ACTION Registry-GWTG (Acute Coronary Treatment and Intervention Outcomes Network Registry–Get With the Guidelines) from 2007 to 2014 were identified. Patients with cardiac arrest, thrombolytic therapy, prior revascularization, or missing demographic or angiographic data were excluded. The primary outcome was all-cause, in-hospital mortality. Secondary outcomes included major adverse cardiovascular events. Demographics, clinical history, presentation, and in-hospital treatments were compared by sex and CAD status (MI-CAD or MINOCA). Mortality and major adverse cardiovascular outcomes were analyzed by age, sex, and CAD status. Among 322 523 patients with MI, MINOCA occurred in 18 918 (5.9%). MINOCA was more common in women than men (10.5% versus 3.4%; P P P P P =0.84). The higher risk of post-MI death among women with MI-CAD was most pronounced at younger ages. Conclusions— MINOCA was associated with lower mortality than MI-CAD. Higher risk of post-MI death among women in comparison to men was restricted to patients with MI-CAD. |
| Databáze: | OpenAIRE |
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