Towards the Development of a Pediatric Ventricular Assist Device
| Autor: | Steven A. Webber, James W. Long, Bradley B. Keller, Marwan A. Simaan, James F. Antaki, Jeff Gardiner, Victor Morell, Bradley Paden, Stijn Vandenberghe, Peter D. Wearden, William R. Wagner, Robert E. Shaddy, Harvey S. Borovetz, Jingchun Wu, Peter C. Kouretas, Stephen F. Badylak, Gordon Jacobs, Dave Paden, Chung M Li, Gill B. Bearnson, Carl N. Johnson, John A. Hawkins, Joshua R. Woolley, P. Khanwilkar, Hiro Tsukui, Shaun T. Snyder, Marina V. Kameneva, Robert L. Kormos, John Kirk, Trevor A. Snyder, J. Robert Boston, Chenguang Diao |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty medicine.medical_treatment Population Biomedical Engineering lcsh:Medicine Biocompatible Materials 03 medical and health sciences 0302 clinical medicine Mixed flow Extracorporeal Membrane Oxygenation Internal medicine medicine Extracorporeal membrane oxygenation Humans Cardiac assist education Child Transplantation education.field_of_study business.industry lcsh:R Treatment options Cell Biology Biocompatible material medicine.disease Ventricular failure 030104 developmental biology Ventricular assist device Cardiology Medical emergency Heart-Assist Devices business 030217 neurology & neurosurgery |
| Zdroj: | Cell Transplantation, Vol 15 (2006) Scopus-Elsevier |
| ISSN: | 1555-3892 0963-6897 |
| Popis: | The very limited options available to treat ventricular failure in children with congenital and acquired heart diseases have motivated the development of a pediatric ventricular assist device at the University of Pittsburgh (UoP) and University of Pittsburgh Medical Center (UPMC). Our effort involves a consortium consisting of UoP, Children's Hospital of Pittsburgh (CHP), Carnegie Mellon University, World Heart Corporation, and LaunchPoint Technologies, Inc. The overall aim of our program is to develop a highly reliable, biocompatible ventricular assist device (VAD) for chronic support (6 months) of the unique and high-risk population of children between 3 and 15 kg (patients from birth to 2 years of age). The innovative pediatric ventricular assist device we are developing is based on a miniature mixed flow turbodynamic pump featuring magnetic levitation, to assure minimal blood trauma and risk of thrombosis. This review article discusses the limitations of current pediatric cardiac assist treatment options and the work to date by our consortium toward the development of a pediatric VAD. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|