Stress Cardiomyopathy in a Patient with Advanced Stage Amyotrophic Lateral Sclerosis
| Autor: | Dora Cerovec, Duško Cerovec, Nenad Lakušić, Ljubica Vincelj Šalković, Ivana Sopek Merkaš, Krunoslav Fučkar, Igor Šesto |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
business.industry Acute ST segment elevation myocardial infarction Internal medicine Cardiomyopathy Cardiology stres kardiomiopatija amiotrofična lateralna skleroza akutni infarkt miokarda s elevacijom ST-segmenta Medicine Amyotrophic lateral sclerosis Cardiology and Cardiovascular Medicine business medicine.disease stress cardiomyopathy amyotrophic lateral sclerosis acute ST-segment elevation myocardial infarction |
| Zdroj: | Cardiologia Croatica Volume 15 Issue 1-2 |
| ISSN: | 1848-5448 1848-543X |
| Popis: | Stres kardiomiopatija entitet je nepoznate etiologije karakteriziran prolaznom sistoličkom disfunkcijom lijeve klijetke i regionalnim poremećajima kontraktilnosti, koji upućuju na infarkt miokarda, ali bez angiografski značajne opstruktivne koronarne bolesti srca. Klinički, u bolesnika se očituje boli u prsima i/ili dispnejom, a promjene u EKG-u upućuju na akutni infarkt miokarda s elevacijom ST-segmenta. Bitan čimbenik razvoja stres kardiomiopatije povišene su razine katekolamina u plazmi kao rezultat hiperaktivnosti simpatikusa izazvane stresnim događajem. Amiotrofična lateralna skleroza (ALS) progresivna je neurodegenerativna bolest koja zahvaća gornji i donji motoneuron, a najčešće završava smrću zbog paralize mišića za disanje i respiratornog zatajenja. U bolesnika s ALSom opisane su povišene razine katekolamina i aktivnosti simpatikusa, što čini rizik za razvoj stres kardiomiopatije. U radu je prikazana bolesnica u uznapredovaloj fazi ALS-a s razvojem stres kardiomiopatije. Stress cardiomyopathy is an entity of unknown etiology characterized by transient systolic dysfunction of the left ventricle and regional wall motion abnormality which suggest myocardial infarction, but with an absence of angiographic evidence of obstructive coronary artery disease. Patients present with chest pain or/and dyspnea, while ECG changes are similar to acute myocardial infarction with ST-elevation. An important factor in the development of stress cardiomyopathy are high catecholamine levels in the blood as a result of the hyperactivity of the sympathetic nervous system caused by a stressful event. Amyotrophic lateral sclerosis (ALS) is an incurable progressive neurodegenerative disease that causes muscle weakness and ultimately ends in death due to respiratory muscle paralysis and respiratory failure. High catecholamine levels and increased sympathetic activity have been described in patients with ALS, which suggests that ALS is a risk factor for developing stress cardiomyopathy. In this article, we present a patient at an advanced stage of ALS who developed stress cardiomyopathy. |
| Databáze: | OpenAIRE |
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