Early recovery from post-traumatic acute respiratory distress syndrome
Autor: | Udo Gottschaldt, M. Seiwerts, Alexander P. Reske, Andreas W. Reske, Dierk Schreiter |
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Rok vydání: | 2006 |
Předmět: |
Male
Pulmonary Atelectasis Time Factors Adolescent Physiology Contusions Brain Edema Atelectasis Pulmonary compliance Wounds Nonpenetrating Positive-Pressure Respiration Physiology (medical) Tidal Volume medicine Humans Lung volumes Hypoxia Lung Lung Compliance Respiratory Distress Syndrome Respiratory distress business.industry Respiratory disease Lung Injury Recovery of Function General Medicine respiratory system medicine.disease Oxygen Pulmonary contusion Respiratory failure Anesthesia Breathing Tomography X-Ray Computed business |
Zdroj: | Clinical Physiology and Functional Imaging. 26:376-379 |
ISSN: | 1475-097X 1475-0961 |
Popis: | Background: To present and discuss the rationale and possible benefits of timely alveolar recruitment in early post-traumatic acute respiratory distress syndrome. Methods: A 17-year-old patient who had sustained blunt thoracic trauma presented with severe hypoxaemia on admission and whole body computed tomography showed pulmonary contusion and substantial bilateral atelectasis. Oxygenation and lung mechanics did not improve with low tidal volume ventilation using high positive end-expiratory pressures (PEEPs). Therefore we applied an alveolar recruitment manoeuvre 7 h after admission. After alveolar recruitment, PEEP was titrated to the lowest level which prevented alveolar derecruitment. Results: Oxygenation and lung compliance improved rapidly and aeration of the entire lung was confirmed by computed tomography 27 h after the recruitment manoeuvre. The patient recovered completely and was discharged after 17 days. Conclusion: Although robust evidence is stilllacking, several lines of evidence suggest potential benefits of timely alveolar recruitment. Patients with early post-traumatic respiratory failure seem to most readily respond to alveolar recruitment manoeuvres and could thus benefit from the gain in functional lung volume and oxygenation. Moreover the probability of ventilator associated complications may be reduced. © 2006 The Authors Journal compilation 2006 Blackwell Publishing Ltd. |
Databáze: | OpenAIRE |
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