Recovery From Exhaustion of the Frank-Starling Mechanism by Mechanical Unloading With a Continuous-Flow Ventricular Assist Device
| Autor: | Koichi Toda, Shigeru Miyagawa, Daisuke Yoshioka, Takashi Daimon, Yoshiki Sawa, Kei Nakamoto, Hiroki Hata, Shunsuke Saito, Yasushi Sakata, Fusako Sera, Yasushi Yoshikawa |
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| Rok vydání: | 2020 |
| Předmět: |
Increased pulmonary capillary wedge pressure
Adult Male medicine.medical_specialty Time Factors Adolescent medicine.medical_treatment Hemodynamics Volume loading 030204 cardiovascular system & hematology Prosthesis Design Ventricular Function Left Prosthesis Implantation 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine Humans 030212 general & internal medicine Device Removal Retrospective Studies Heart Failure Frank–Starling law of the heart Exercise Tolerance business.industry Continuous flow Models Cardiovascular Repeated measures design Increased cardiac output General Medicine Recovery of Function Middle Aged equipment and supplies Adaptation Physiological Treatment Outcome Ventricular assist device Cardiology Female Heart-Assist Devices Cardiology and Cardiovascular Medicine business |
| Zdroj: | Circulation journal : official journal of the Japanese Circulation Society. 84(7) |
| ISSN: | 1347-4820 |
| Popis: | BACKGROUND We describe our original left ventricular assist device (LVAD) speed ramp and volume loading test designed to evaluate native heart function under continuous-flow LVAD support.Methods and Results:LVAD speed was decreased in 4 stages from the patient's optimal speed to the minimum setting for each device. Under minimal LVAD support, patients were subjected to saline loading (body weight [kg]×10 mL in 15 min). Echocardiographic and hemodynamic data were obtained at each stage of the LVAD speed ramp and every 3 min during saline loading. Patients were divided into Recovery (with successful LVAD removal; n=8) and Non-recovery (others; n=31) groups. During testing, increased pulmonary capillary wedge pressure caused by volume loading was milder in the Recovery than Non-recovery group (repeated measures analysis of variance; group effect, P=0.0069; time effect, P |
| Databáze: | OpenAIRE |
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