Use of Vitek 2 Antimicrobial Susceptibility Profile To Identify mecC in Methicillin-Resistant Staphylococcus aureus
| Autor: | Kathy E. Raven, Edward J. P. Cartwright, Theodore Gouliouris, Robert Skov, Gavin K. Paterson, Mark A. Holmes, Sharon J. Peacock, Bruno Pichon, Ewan M. Harrison, Angela Kearns, Julian Parkhill, M. Estée Török, Anders Rhod Larsen, Giles Edwards |
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| Rok vydání: | 2013 |
| Předmět: |
Methicillin-Resistant Staphylococcus aureus
Microbiology (medical) 0303 health sciences 030306 microbiology business.industry Antimicrobial susceptibility Bacteriology Microbial Sensitivity Tests Gold standard (test) biochemical phenomena metabolism and nutrition bacterial infections and mycoses medicine.disease_cause Sensitivity and Specificity Methicillin-resistant Staphylococcus aureus Microbiology 03 medical and health sciences Clinical microbiology Staphylococcus aureus medicine Screening method Humans business 030304 developmental biology |
| Zdroj: | Journal of Clinical Microbiology |
| ISSN: | 1098-660X 0095-1137 |
| DOI: | 10.1128/jcm.00847-13 |
| Popis: | The emergence of mecC methicillin-resistant Staphylococcus aureus (MRSA) poses a diagnostic challenge for clinical microbiology laboratories. Using the Vitek 2 system, we tested a panel of 896 Staphylococcus aureus isolates and found that an oxacillin-sensitive/cefoxitin-resistant profile had a sensitivity of 88.7% and a specificity of 99.5% for the identification of mecC MRSA isolates. The presence of the mecC gene, determined by bacterial whole-genome sequencing, was used as the gold standard. This profile could provide a zero-cost screening method for identification of mecC -positive MRSA strains. |
| Databáze: | OpenAIRE |
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