Bone loss markers in the earliest Pacific Islanders
| Autor: | Geoffrey Clark, Frédérique Valentin, Christina Vrahnas, Natalie A. Sims, Mark J. Tobin, Jitraporn Vongsvivut, Justyna J. Miszkiewicz |
|---|---|
| Přispěvatelé: | Archéologies et Sciences de l'Antiquité (ArScAn), Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris Nanterre (UPN)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Ministère de la Culture et de la Communication (MCC)-Institut national de recherches archéologiques préventives (Inrap)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Male Biological anthropology Osteoporosis [SHS.ANTHRO-BIO]Humanities and Social Sciences/Biological anthropology Carbonates Physiology 0302 clinical medicine Bone Density Spectroscopy Fourier Transform Infrared Femur Child History Ancient Aged 80 and over education.field_of_study Multidisciplinary Microscopy Confocal Middle Aged medicine.anatomical_structure Archaeology Child Preschool Pacific islanders Medicine Female Adult Surface Properties Science Population 030209 endocrinology & metabolism Biology Bone resorption Poor quality Polynesia Article Phosphates 03 medical and health sciences medicine Humans Obesity Bone Resorption education Bone Aged Infant Histology medicine.disease 030104 developmental biology Cortical bone Biomarkers Synchrotrons |
| Zdroj: | Scientific Reports Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-83264-3⟩ Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021) Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-83264-3⟩ |
| ISSN: | 2045-2322 |
| Popis: | Kingdom of Tonga in Polynesia is one of the most obese nations where metabolic conditions, sedentary lifestyles, and poor quality diet are widespread. These factors can lead to poor musculoskeletal health. However, whether metabolic abnormalities such as osteoporosis occurred in archaeological populations of Tonga is unknown. We employed a microscopic investigation of femur samples to establish whether bone loss afflicted humans in this Pacific region approximately 3000 years ago. Histology, laser confocal microscopy, and synchrotron Fourier-transform infrared microspectroscopy were used to measure bone vascular canal densities, bone porosity, and carbonate and phosphate content of bone composition in eight samples extracted from adult Talasiu males and females dated to 2650 BP. Compared to males, samples from females had fewer vascular canals, lower carbonate and phosphate content, and higher bone porosity. Although both sexes showed evidence of trabecularised cortical bone, it was more widespread in females (35.5%) than males (15.8%). Our data suggest experiences of advanced bone resorption, possibly as a result of osteoporosis. This provides first evidence for microscopic bone loss in a sample of archaeological humans from a Pacific population widely afflicted by metabolic conditions today. |
| Databáze: | OpenAIRE |
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