Molecular-Iodine-Catalyzed Cyclization of 2-Alkynylanilines via Iodocyclization-Protodeiodination Sequence

Autor:	Akio Saito, Keiichi Noguchi, Yuichiro Takeda, Ryota Kajihara, Naoko Kobayashi
Rok vydání:	2017
Předmět:	Tandem 010405 organic chemistry Organic Chemistry chemistry.chemical_element 010402 general chemistry Iodine 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences Catalysis chemistry.chemical_compound Aniline chemistry Physical and Theoretical Chemistry Sequence (medicine)
Zdroj:	Organic letters. 19(24)
ISSN:	1523-7052
Popis:	Molecular iodine catalyzes a cyclization of N-aryl-2-alkynylanilines, which proceeds through the iodocyclization of 2-alkynylanilines followed by the protodeiodination of the iodocyclized intermediates at room temperature. Furthermore, the molecular iodine catalysis can be applied to the cascade cyclization of 2-(enynyl)aniline and to the tandem cyclization–addition reaction of 2-alkynylanilines with α,β-enones.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d944926f46bc6a57469c82c38bfd5c51 https://pubmed.ncbi.nlm.nih.gov/29185766 Zobrazit plný text záznamu