Recently reported biological activities of pyrazole compounds
| Autor: | Maurício S. dos Santos, Ana Gabriella Carvalho Miguita, Alice M. R. Bernardino, Nubia Boechat, Jéssica V. Faria, Percilene Fazolin Vegi |
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| Rok vydání: | 2017 |
| Předmět: |
Research groups
Antifungal Agents Clinical Biochemistry Pharmaceutical Science Antineoplastic Agents Pyrazole 010402 general chemistry 01 natural sciences Biochemistry Antiviral Agents chemistry.chemical_compound Broad spectrum Rimonabant Drug Discovery Phenylbutazone medicine Organic chemistry Animals Humans Molecular Biology chemistry.chemical_classification Analgesics 010405 organic chemistry Organic Chemistry Anti-Inflammatory Agents Non-Steroidal Combinatorial chemistry 0104 chemical sciences Anti-Bacterial Agents chemistry Molecular Medicine Azole Pyrazoles medicine.drug |
| Zdroj: | Bioorganicmedicinal chemistry. 25(21) |
| ISSN: | 1464-3391 |
| Popis: | The pyrazole nucleus is an aromatic azole heterocycle with two adjacent nitrogen atoms. Pyrazole derivatives have exhibited a broad spectrum of biological activities, and approved pyrazole-containing drugs include celecoxib, antipyrine, phenylbutazone, rimonabant, and dipyrone. Many research groups have synthesized and evaluated pyrazoles against several biological agents. This review examines recent publications relating the structures of pyrazoles with their corresponding biological activities. |
| Databáze: | OpenAIRE |
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