Central nervous side effects following ifosfamide monotherapy of advanced renal carcinoma
| Autor: | W. Queisser, R Fiene, M. E. Heim, E. Wolpert, E. Schick |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty MEDLINE Subjective improvement Central Nervous System Diseases Internal medicine medicine Humans Ifosfamide Cyclophosphamide Aged Hematology business.industry Mental Disorders General Medicine Middle Aged Kidney Neoplasms Surgery Oncology Female business Renal carcinoma medicine.drug |
| Zdroj: | Journal of Cancer Research and Clinical Oncology. 100:113-116 |
| ISSN: | 1432-1335 0171-5216 |
| DOI: | 10.1007/bf00405909 |
| Popis: | Ten patients with advanced renal carcinoma were treated by ifosfamide (50-60 mg/kd/day x 5 days). The treatment was repeated every 4 weeks and continued until progression appeared. Two patients came into partial remission, two had subjective improvement, and six did not respond. Seven patients developed acute psychopathological symptoms during the first ifosfamide-cycle. Five patients had visual and paranoid hallucinations, four patients were completely confused. Follow-up for up to 10 weeks showed a persisting organic brain syndrome in five patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink