Effects of supplementation with kombucha and green banana flour on Wistar rats fed with a cafeteria diet
| Autor: | Solange Maria Cottica, Marianela Díaz Urrutia, Rafaela Beatriz Menegusso, Adriana Gadioli Tarone, Rafael Dewes Lenz, Amanda Gemelli Ramos, Daniela Miotto Bernardi, Cinthia Baú Betim Cazarin, Sóstenez Alexandre Vessaro Silva, Mateus Gemelli Ramos |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Kombucha Hepatic steatosis Antioxidant Science (General) medicine.medical_treatment Functional foods Population Cafeteria Feed conversion ratio 03 medical and health sciences Q1-390 0302 clinical medicine Antioxidant activity Hypercaloric diet medicine Food science education H1-99 education.field_of_study Multidisciplinary biology medicine.diagnostic_test biology.organism_classification Social sciences (General) 030104 developmental biology Cafeteria diet Composition (visual arts) medicine.symptom Lipid profile Weight gain 030217 neurology & neurosurgery Research Article |
| Zdroj: | Heliyon Heliyon, Vol 7, Iss 5, Pp e07081-(2021) |
| ISSN: | 2405-8440 |
| Popis: | Introduction With the increase of chronic diseases as a consequence of the population's eating habits, there is also a growing interest in foods rich in bioactive compounds capable of mitigating these diseases. Thus, this study aimed to evaluate the effects of supplementation with kombucha and green banana flour (GBF) on Wistar rats fed with cafeteria diet (CAF). Methods The animals were randomized into five groups of seven animals each, which were fed with the following diets: Treatment 1 (T1): Control treatment/commercial feed; Treatment 2 (T2): cafeteria diet (CAF); Treatment 3 (T3): CAF + kombucha; Treatment 4 (T4): CAF + green banana flour (GBF); Treatment 5 (T5): CAF + GBF + kombucha. Daily weight gain, daily food consumption, feed conversion, blood glucose, total cholesterol and fractions, triglycerides, liver enzymes, antioxidant activity, and body composition were evaluated. Results T5 presented lower feed intake and less weight gain. Liver histology revealed vacuolization in all treatments except T1, which was confirmed by the results of liver enzymes. There was no increase in blood glucose, and changes were observed in the lipid profile of the animals. T1 had the lowest body fat and the highest protein levels. Differences were observed for the antioxidant capacity in the liver of animals among treatments. Conclusion The intake of cafeteria diet altered the lipid and liver profile of the animals and the consumption of kombucha and GBF did not prevent these changes. The high polyphenols level of kombucha did not exert a hepatoprotective effect as an antioxidant. However, this supplementation generated greater satiety in the animals, leading to less weight gain until the end of the experiment. Functional foods; Cafeteria diet; Hepatic steatosis; Antioxidant activity; Hypercaloric diet |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|