The difficult-to-treat, therapy-resistant cough: why are current cough treatments not working and what can we do?
| Autor: | Lorcan McGarvey |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Treatment response Therapy resistant Opiate therapy Alternative medicine Psychological intervention Drug Resistance Speech Therapy law.invention Randomized controlled trial law Intervention (counseling) Medicine Animals Humans Pharmacology (medical) Intensive care medicine Randomized Controlled Trials as Topic business.industry Biochemistry (medical) Antidepressive Agents Anti-Bacterial Agents Analgesics Opioid Antitussive Agents Cough Chronic Disease Practice Guidelines as Topic Physical therapy Patient Compliance Guideline Adherence business Speech-Language Pathology |
| Zdroj: | Pulmonary pharmacologytherapeutics. 26(5) |
| ISSN: | 1522-9629 |
| Popis: | Cough can persist despite exhaustive diagnostic and therapeutic effort and has been termed 'idiopathic' or 'unexplained' but perhaps 'difficult to treat' cough is a more appropriate description. In this article the reasons for poor treatment response are discussed. These include a lack of physician fidelity to management guidelines, patient non-adherence and the lack of effective medicines. A number of randomized controlled trials have been undertaken including low dose opiate therapy, the use of a speech pathology intervention, oral antibiotics and antidepressants. The success or otherwise of such interventions will be discussed. A number of approaches to deal with the problem of 'difficult to treat cough' will be considered. |
| Databáze: | OpenAIRE |
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