Antimicrobial resistance increased over an 8‐year period in Enterobacteriaceae cultured from canine urine samples
| Autor: | A. M. Ríos Boeta, N. Ruiz Duro, C. Fernández Pérez, Robert E. Shiel, P. J. Guzmán Ramos, G. Ortiz‐Díez, J. I. Ballester Aguado, M. R. Perlado Chamizo |
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| Rok vydání: | 2021 |
| Předmět: |
Veterinary medicine
Microbiological culture 040301 veterinary sciences Prevalence Microbial Sensitivity Tests Urine 0403 veterinary science symbols.namesake Dogs Antibiotic resistance Enterobacteriaceae Drug Resistance Bacterial Animals Medicine Clinical significance Dog Diseases Poisson regression Small Animals Retrospective Studies business.industry 0402 animal and dairy science 04 agricultural and veterinary sciences Antimicrobial 040201 dairy & animal science Confidence interval Anti-Bacterial Agents Urinary Tract Infections symbols business |
| Zdroj: | Journal of Small Animal Practice. 62:279-285 |
| ISSN: | 1748-5827 0022-4510 |
| Popis: | OBJECTIVES The aims of the present study were to describe the prevalence of positive urinary bacterial culture in dogs, to identify the most commonly isolated microorganisms and to analyse changes in antimicrobial susceptibility patterns over time. MATERIAL AND METHODS A retrospective case series was performed using culture and susceptibility results from canine urine samples collected between January 2010 and December 2017. The presence or absence of infection, identity of the bacterium with heaviest growth, and susceptibility profile were recorded for each sample. Trends in the frequency of positive culture and antimicrobial resistance were assessed by Poisson regression modelling. Prevalence rate ratio and 95% confidence interval were reported for resistance to each antimicrobial. RESULTS A positive urine culture was documented in 771 (22.5%) of 3420 samples. Escherichia coli was the most commonly isolated microorganism. There was no significant increase in the frequency of positive bacterial culture over the study period (prevalence rate ratio 0.98; 95% confidence interval: 0.92 to 1.0). Overall, there was an increase in antimicrobial resistance within Enterobacteriaceae from 5.2 to 35.6%. The prevalence of multidrug-resistant bacteria varied from year to year throughout the study period. However, the Poisson regression model identified a significant increase in the frequency of multidrug-resistant Enterobacteriaceae over this period, averaging approximately 22% per year (prevalence rate ratio 1.22, 95% confidence interval: 1.06 to 1.42). CLINICAL SIGNIFICANCE The significant increase in antimicrobial resistance observed in this study is concerning and may have implications for veterinary and public health. Appropriate measures, such as antibiotic stewardship programmes, should be implemented to address increasing antimicrobial resistance. |
| Databáze: | OpenAIRE |
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