Adjunctive effect of orthokeratology and low dose atropine on axial elongation in fast-progressing myopic children—A preliminary retrospective study
| Autor: | Jiaqi Zhou, Zhi Chen, Xingtao Zhou, Xiao-mei Qu, Shengmei Huang, Feng Xue |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Atropine
Male Mydriatics Refractive error medicine.medical_specialty medicine.medical_treatment Administration Ophthalmic Spherical equivalent 03 medical and health sciences 0302 clinical medicine Ophthalmology Myopia medicine Humans Child Retrospective Studies business.industry Low dose Orthokeratology Retrospective cohort study General Medicine medicine.disease Combined Modality Therapy Axial elongation Axial Length Eye Treatment Outcome Child Preschool 030221 ophthalmology & optometry Female Ophthalmic Solutions Elongation business Orthokeratologic Procedures 030217 neurology & neurosurgery Optometry medicine.drug |
| Zdroj: | Contact Lens and Anterior Eye. 42:439-442 |
| ISSN: | 1367-0484 |
| DOI: | 10.1016/j.clae.2018.10.026 |
| Popis: | To investigate the adjunctive effect of orthokeratology (ortho-k) and low-dose atropine eye drops on axial length elongation in fast-progressing myopic children.Axial elongation in 60 eyes of 60 subjects who completed two years of ortho-k treatment was retrospectively reviewed. They were aged between 5.6-11.6 (mean, 8.3 ± 1.5) years old when they started ortho-k treatment. During their first year of ortho-k treatment (Phase One), they all demonstrated a faster than 0.25 mm/yr axial elongation rate. They were then treated with nightly 0.01% atropine in addition to ortho-k treatment for another year (Phase Two). Annual axial elongation rates before and after atropine treatment were compared.Baseline spherical equivalent refractive error was -2.65 ± 1.08 DS and axial length was 24.34 ± 0.92 mm for the study cohort. The mean axial elongation rate was 0.46 ± 0.16 mm/yr during Phase One, being significantly faster in younger children (t = -4.920, P 0.001). When atropine was added, annual axial elongation rate significantly decreased to 0.14 ± 0.14 mm/yr (t = -11.988, P 0.001), and those who were fast progressors in Phase One had a greater reduction in the rate of axial elongation during Phase Two (t = -8.052, P 0.001).Axial elongation rate is faster in younger children undergoing ortho-k treatment. For fast myopia progressors, low dose atropine may significantly slow axial elongation in addition to ortho-k's treatment effect. Those who have faster axial elongation after ortho-k treatment will benefit more from the addition of low dose atropine, regardless of their refractive error and age. |
| Databáze: | OpenAIRE |
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