Antimicrobial therapy for cutaneous infections
| Autor: | Richard L. Dobson |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
Impetigo medicine.drug_class Antibiotics Dermatology Bacitracin Skin Diseases medicine Immune Tolerance Dermatomycoses Humans Cutaneous infections business.industry Fatty Acids Bacterial Infections medicine.disease Antimicrobial Anti-Bacterial Agents Penicillin Sulfathiazole Mupirocin Ecthyma Immunology Staphylococcal Skin Infections business medicine.drug |
| Zdroj: | Journal of the American Academy of Dermatology. 22(5 Pt 1) |
| ISSN: | 0190-9622 |
| Popis: | In its simplest terms, a cutaneous infection represents the ability of an organism to overcomesome or all of the numerous factors that collectivelymake up what is referred to as "host resistance." This viewpoint dominated the thinking of dermatologists in the not-so-distant past. For example, in the 1954 (the year I began my training in dermatology) edition of their textbook, Ormsby and Montgomery' define impetigo as "a pus infection, the result of the transmission to the skin of an infection of streptococci, staphylococci, or both." Ecthyma was, in their opinion, "of the same nature as impetigo, but of deeper situation." The recommended treatment for these infections was entirely topical-ammoniated mercury ointment, neomycin cream alone or in combination with bacitracin, and polymyxinor gentian violet solution were the treatments of choice. For reasons that are still unclear, they stated that the systemic administration of "sulfathiazole or penicillin is no longer recommended,"and this edict was generally followed at that time. In the decades that followed, we have witnessed an enormous advance in our understanding of the pathogenesis of cutaneous infections, and we now have available an array of antibiotic agents that kill or inhibit the growth of all classes of organisms from viral to protozoan. Despite these advances, it is somewhat paradoxic that today's cutaneous infections often present more significant and difficult problems both diagnostically and therapeutically |
| Databáze: | OpenAIRE |
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