Survey of Slaughtered Pigs for Occurrence of Ochratoxin A and Porcine Nephropathy in Serbia
| Autor: | Srđan Stefanović, Verica Jurić, Saša Janković, Milijan Jovanović, Dragan Milićević |
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| Rok vydání: | 2008 |
| Předmět: |
pig
Ochratoxin A Pathology medicine.medical_specialty Necrosis tissues nephropathy 040301 veterinary sciences Porcine nephropathy Article Catalysis Nephropathy lcsh:Chemistry 0403 veterinary science Inorganic Chemistry 03 medical and health sciences chemistry.chemical_compound Edema Medicine Physical and Theoretical Chemistry lcsh:QH301-705.5 Molecular Biology Spectroscopy 030304 developmental biology 0303 health sciences Kidney business.industry Incidence (epidemiology) Organic Chemistry 04 agricultural and veterinary sciences General Medicine medicine.disease 3. Good health Computer Science Applications medicine.anatomical_structure lcsh:Biology (General) lcsh:QD1-999 chemistry Vacuolization medicine.symptom business |
| Zdroj: | International Journal of Molecular Sciences International Journal of Molecular Sciences, Vol 9, Iss 11, Pp 2169-2183 (2008) International Journal of Molecular Sciences; Volume 9; Issue 11; Pages: 2169-2183 |
| ISSN: | 1422-0067 |
| DOI: | 10.3390/ijms9112169 |
| Popis: | Samples of blood, kidney and liver were randomly selected from slaughtered pigs (n=90) and analyzed for ochratoxin A by HPLC. In addition, in order to obtain information on the occurrence of nephropathy, histological examinations were carried out. Of the 90 liver samples, 26.6% contained OTA in the range of 0.22-14.5 ng/g. The incidence of OTA in serum and kidney were very similar (31%, 33.3%), with a maximum concentration of 220.8 ng/mL, and 52.5 ng/g, respectively. Histopathological examination of kidneys confirmed tubulopathies with edema and cell vacuolization. In addition, hemorrhages and necrosis of proximal kidney tubules’ cells were found. |
| Databáze: | OpenAIRE |
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