Autologous Chondrocyte Implantation for Talar Osteochondral Lesions: Comparison Between 5-Year Follow-Up Magnetic Resonance Imaging Findings and 7-Year Follow-Up Clinical Results
| Autor: | Laura Ramponi, Gherardo Pagliazzi, Roberto Buda, Milva Battaglia, Francesca Vannini |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Cartilage Articular Male medicine.medical_specialty Time Factors 5 year follow up Transplantation Autologous Statistics Nonparametric Talus Cohort Studies Young Adult 03 medical and health sciences Chondrocytes 0302 clinical medicine Defect filling medicine Humans Orthopedics and Sports Medicine Range of Motion Articular Autologous chondrocyte implantation Pain Measurement Retrospective Studies Aofas score 030222 orthopedics medicine.diagnostic_test business.industry Hyaline cartilage Magnetic resonance imaging 030229 sport sciences Middle Aged Magnetic Resonance Imaging Surgery Treatment Outcome medicine.anatomical_structure Linear Models Female Ankle business Cartilage Diseases Ankle Joint Follow-Up Studies |
| Zdroj: | The Journal of Foot and Ankle Surgery. 57:221-225 |
| ISSN: | 1067-2516 |
| DOI: | 10.1053/j.jfas.2017.05.013 |
| Popis: | Autologous chondrocyte implantation (ACI) is an established surgical procedure that has provided satisfactory results. The aim of the present study was to correlate the clinical outcomes of a series of 20 patients treated by ACI at a 7-year follow-up examination with the magnetic resonance imaging (MRI) T2-mapping 5-year follow-up findings. We evaluated 20 patients using the American Orthopaedic Foot and Ankle Society (AOFAS) score preoperatively and the established follow-up protocol until 87.2 ± 14.5 months. MRI T2-mapping sequences were acquired at the 5-year follow-up examination. At the MRI examination (60 ± 12 months), the mean AOFAS score improved from 58.7 ± 15.7 to 83.9 ± 18.4. At the final follow-up examination at 87.2 ± 14.5 months, the AOFAS score was 90.9 ± 12.7 (p = .0005). Those patients who experienced an improvement between 5 and 7 years after surgery had a significant greater percentage of T2-map value of 35 to 45 ms (hyaline cartilage) compared with those patients who did not improve (p = .038). MRI T2 mapping was shown to be a valuable tool capable of predicting reproducible clinical outcomes after ACI even 7 years after surgery. The quality of the regenerated tissue and the degree of defect filling became statistically significant to the clinical results at the final follow-up examination. |
| Databáze: | OpenAIRE |
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