The association between low lean mass and osteoporosis increases the risk of weakness, poor physical performance and frailty in Brazilian older adults: data from SARCOS study
| Autor: | Monica Maria Cartocci, Antonio Carlos de Camargo Carvalho, Alberto Frisoli, Jairo Lins Borges, Eliene Cezario de Lima, Sheila McNeill Ingham, Angela Tavares Paes |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Weakness Sarcopenia Osteoporosis Medicine (miscellaneous) 030209 endocrinology & metabolism 03 medical and health sciences Geriatric cardiology 0302 clinical medicine Internal medicine medicine Humans Geriatric Assessment Aged Aged 80 and over 030109 nutrition & dietetics Nutrition and Dietetics Frailty business.industry Physical Functional Performance medicine.disease Impaired mobility Preferred walking speed Cross-Sectional Studies Physical performance Lean body mass Female medicine.symptom business Brazil |
| Zdroj: | European journal of clinical nutrition. 75(3) |
| ISSN: | 1476-5640 |
| Popis: | PURPOSE To characterize the phenotypes of older adults with low lean mass and osteoporosis, concomitantly or isolated, in regards to poor physical performance and frailty status. DESIGN Cross-sectional analysis of the SARCopenia and OSteoporosis in Older Adults with Cardiovascular Diseases Study (SARCOS). SETTING Outpatient geriatric cardiology clinic. PARTICIPANTS AND METHOD 385 older adults underwent DXA analysis. Low lean mass was diagnosed according to FNIH and low BMD by a T-score ≤ -2.5 SD. Subjects were grouped into: I-Low lean mass and Osteoporosis (LLMO); II-Low lean mass (LLM); III-Osteoporosis (OP), and IV-Controls. Poor physical performance was diagnosed by weakness or slow walking speed or impaired mobility. Frailty was diagnosed by CHS criteria. RESULTS The mean age was 78.22 ± 7.16 years. The prevalence of LLMO, LLM, and OP were 14.8%, 39.5%, and 19.2%, respectively. LLMO subjects were older, predominantly women, with a high percentage of body fat (HTBF). LLM was represented by obese men, while individuals with OP were preferably women, older and leaner. In a regression analyses, LLMO presented an OR: 6.42 (2.63‒15.65; p |
| Databáze: | OpenAIRE |
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