Pinealectomy and blindness during pregnancy in the rat
Autor: | José Paixão de Souza, Neuza O.G. Silva, Amaury Teixeira Leite Andrade, Martha de Oliveira Guerra, Calina S. Guimarães |
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Rok vydání: | 1973 |
Předmět: |
medicine.medical_specialty
Transplacental transmission medicine.medical_treatment Pinealectomy Blindness Pineal Gland Pregnancy Medicine Animals Sex organ Fetal Death biology business.industry Transmission (medicine) Obstetrics Obstetrics and Gynecology Transplacental medicine.disease Rats Pregnancy Complications Term Infant Immunoglobulin M biology.protein Female business |
Zdroj: | American journal of obstetrics and gynecology. 115(4) |
ISSN: | 0002-9378 |
Popis: | Little alludes to the possibility of transplacental transmission of herpes simplex, and there is a paucity of data regarding the efficacy of abdominal delivery.? Amstey’ reviewed the neonatal outcome of infants delivered abdominally of mothers with genital herpetic lesions. He cites a case wherein a term infant died from herpes infection after abdominal delivery although the membranes were intact. This case is interesting from several standpoints. Advanced and marked scarring lesions at birth suggest intrauterine infection of a minimum of one to two weeks’ duration. Positive Immunoglobulin M antibodies to herpes suggest further an infection of at least two weeks’ duration prior to delivery. Since the infant was delivered within 24 hours of membrane rupture, an ascending and contact mode of transmission may be excluded. The foregoing presents the likelihood of transplacental dissemination, which may influence clinical judgment regarding abdominal delivery in selected cases. |
Databáze: | OpenAIRE |
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