Different hormonal patterns in human menopausal gonadotropin-treated, clomiphene citrate-treated, and untreated conception cycles
| Autor: | Keiichi Kato, Heinz G. Bohnet, Freimut A. Leidenberger, Michael Trapp, Hans Ch. Weise |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Adult
Ovulation medicine.medical_specialty Menotropins medicine.drug_class media_common.quotation_subject Thyrotropin Biology Chorionic Gonadotropin Clomiphene Ovarian Follicle Ovulation Induction Pregnancy Clomifene Internal medicine Hydroxyprogesterones medicine Humans Testosterone Progesterone Menstrual cycle media_common Estradiol Dehydroepiandrosterone Sulfate 17-alpha-Hydroxyprogesterone Obstetrics and Gynecology Dehydroepiandrosterone Hormones Prolactin Endocrinology medicine.anatomical_structure Reproductive Medicine Estrogen Fertilization Female Gonadotropin Corpus luteum medicine.drug |
| Zdroj: | Fertility and Sterility. 45:469-474 |
| ISSN: | 0015-0282 |
| DOI: | 10.1016/s0015-0282(16)49271-x |
| Popis: | Serum concentrations of seven different hormones were analyzed during 189 singleton conception cycles. One hundred nine women were treated with human menopausal gonadotropin (hMG), 52 women received clomiphene citrate (CC), and 28 became pregnant spontaneously. Serum progesterone (P) levels in hMG-treated women started to increase on day 18 of the cycle and reached peak concentrations between days 28 and 32 of the cycle. Serum estradiol (E2) concentrations paralleled the P patterns. In hMG-treated women, there were significant correlations between serum E2 and P concentrations and the number of the mature follicles observed before ovulation (both P less than 0.01). CC-treated and spontaneous conception cycles revealed significantly lower serum levels of P, E2, testosterone, 17 alpha-hydroxyprogesterone, and prolactin, compared with hMG-treated cycles (P less than 0.05). Elevations of the gonadal steroids in hMG-treated women possibly reflect the multiple corpora lutea formed after multiple ovulations. |
| Databáze: | OpenAIRE |
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