Insulin as a model to teach three-dimensional structure of proteins
| Autor: | João Rocha, Gabriela Luisa Schmitz, Cláudia S. Oliveira, Pablo A. Nogara |
|---|---|
| Přispěvatelé: | CAPES, CNPq., Capes, CNPq |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Structure (mathematical logic)
Educação em bioquímica estudantes de graduação modelos de proteínas Computer science education biochemistry education protein models undergraduate students lcsh:Education (General) lcsh:Biochemistry Simple (abstract algebra) Automotive Engineering Mathematics education lcsh:QD415-436 Construct (philosophy) lcsh:L7-991 3D models Protein |
| Zdroj: | Revista de Ensino de Bioquímica; v. 15, n. 2 (2017): REB (Jul-Dez); 114-130 Revista de Enseñanza de Bioquímica; v. 15, n. 2 (2017): REB (Jul-Dez); 114-130 Journal of Biochemistry Education; v. 15, n. 2 (2017): REB (Jul-Dez); 114-130 Revista de Ensino de Bioquímica Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq) instacron:SBBQM Journal of Biochemistry Education, Vol 15, Iss 2, Pp 114-130 (2018) |
| ISSN: | 2318-8790 |
| Popis: | Proteins are the most ubiquitous macromolecules found in the living cells and have innumerous physiological functions. Therefore, it is fundamental to build a solid knowledge about the proteins three dimensional structure to better understand the living state. The hierarchical structure of proteins is usually studied in the undergraduate discipline of Biochemistry. Here we described pedagogical interventions designed to increase the preservice teacher chemistry students’ knowledge about protein structure. The activities were made using alternative and cheap materials to encourage the application of these simple methodologies by the future teachers in the secondary school. From the primary structure of insulin chains, students had to construct a three-dimensional structure of insulin. After the activities, the students highlighted an improvement of their previous knowledge about proteins structure. The construction of a tridimensional model together with other activities seems to be an efficient way to promote the learning about the structure of proteins to undergraduate students. The methodology used was inexpensiveness and simple and it can be used both in the university and in the high-school.Proteins are the most ubiquitous macromolecules found in the living cells and have innumerous physiological functions. Therefore, it is fundamental to build a solid knowledge about the proteins three dimensional structure to better understand the living state. The hierarchical structure of proteins is usually studied in the undergraduate discipline of Biochemistry. Here we described pedagogical interventions designed to increase the preservice teacher chemistry students’ knowledge about protein structure. The activities were made using alternative and cheap materials to encourage the application of these simple methodologies by the future teachers in the secondary school. From the primary structure of insulin chains, students had to construct a three-dimensional structure of insulin. After the activities, the students highlighted an improvement of their previous knowledge about proteins structure. The construction of a tridimensional model together with other activities seems to be an efficient way to promote the learning about the structure of proteins to undergraduate students. The methodology used was inexpensiveness and simple and it can be used both in the university and in the high-school. As proteínas são macromoléculas amplamente encontradas nas células e possuem inúmeras funções fisiológicas. Consequentemente, é de fundamental construir um conhecimento sólido sobre estrutura tridimensional das proteínas. As estruturas proteicas são geralmente estudadas durante a graduação na disciplina de Bioquímica. Neste trabalho descrevemos intervenções pedagógicas planejadas para aumentar o conhecimento de estudantes de Química licenciatura sobre a estrutura de proteínas. As atividades foram realizadas utilizando materiais baratos para encorajar a sua implementação no ensino médio pelos futuros professores. A partir da estrutura primária da insulina, os estudantes construíram a estrutura tridimensional desta proteína. Após as atividades, os estudantes destacaram uma melhora nos seus conhecimentos prévios sobre a estrutura das proteínas. A construção de um modelo tridimensional juntamente com outras atividades parece ser uma maneira eficiente de promover o aprendizado sobre a estrutura de proteínas aos estudantes de graduação. A metodologia utilizada foi simples e de baixo custo e pode ser utilizada tanto no nível universitário como no nível do ensino médio. |
| Databáze: | OpenAIRE |
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