Defining Dysbiosis in Inflammatory Bowel Disease
Autor: | Renske J. de Jong, Caspar Ohnmacht |
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Rok vydání: | 2019 |
Předmět: |
0301 basic medicine
Effector Immunology Inflammatory Bowel Diseases Biology medicine.disease Inflammatory bowel disease 3. Good health 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Infectious Diseases Human disease Immunity RAR-related orphan receptor gamma 030220 oncology & carcinogenesis medicine Immunology and Allergy Colitis Dysbiosis |
Zdroj: | Immunity Immunity 50, 8-10 (2019) |
ISSN: | 1074-7613 |
DOI: | 10.1016/j.immuni.2018.12.028 |
Popis: | In this issue of Immunity, Britton et al. (2019) demonstrate that the colonization of germ-free mice with microbiotas from inflammatory bowel disease patients induces an altered ratio of ROR gamma t(+) regulatory T cells to T(h17) effector cells and recapitulates human disease severity in colitis-susceptible mice. |
Databáze: | OpenAIRE |
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