Confinement-induced self-organization in growing bacterial colonies
| Autor: | Daniel J. G. Pearce, Zhihong You, Luca Giomi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Physics
Self-organization 0303 health sciences Multidisciplinary FOS: Physical sciences Condensed Matter - Soft Condensed Matter 01 natural sciences Viscoelasticity Quantitative Biology::Cell Behavior 03 medical and health sciences Molecular dynamics Classical mechanics Biological Physics (physics.bio-ph) 0103 physical sciences Stress relaxation Pairwise sequence alignment Soft Condensed Matter (cond-mat.soft) Physics - Biological Physics 010306 general physics Anisotropy 030304 developmental biology |
| Zdroj: | Science Advances, 7(4). American Association for the Advancement of Science (AAAS) |
| ISSN: | 2375-2548 |
| Popis: | We investigate the emergence of global alignment in colonies of dividing rod-shaped cells under confinement. Using molecular dynamics simulations and continuous modeling, we demonstrate that geometrical anisotropies in the confining environment give rise to imbalance in the normal stresses, which, in turn, drives a collective rearrangement of the cells. This behavior crucially relies on the colony's solid-like mechanical response at short time scales and can be recovered within the framework of active hydrodynamics upon modeling bacterial colonies as growing viscoelastic gels characterized by Maxwell-like stress relaxation. Comment: 10 pages, 8 figures |
| Databáze: | OpenAIRE |
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