Use of a modified microplate bioassay method to investigate antibacterial activity in the Peruvian medicinal plant Peperomia galioides
| Autor: | Miwako Kondo, Gerald B. Hammond, Mary E. Heitzman, Catherine C. Neto, Richard D. Langfield, Frank J. Scarano |
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| Rok vydání: | 2004 |
| Předmět: |
Pharmacology
Staphylococcus aureus Plants Medicinal Peperomia galioides Plant Stems biology Traditional medicine Plant Extracts food and beverages Microbial Sensitivity Tests Pharmacognosy biology.organism_classification Peperomia Anti-Bacterial Agents Plant Leaves Staphylococcus epidermidis Peru Drug Discovery Botany Bioassay Medicinal plants Antibacterial activity Antibacterial agent |
| Zdroj: | Journal of Ethnopharmacology. 94:279-281 |
| ISSN: | 0378-8741 |
| DOI: | 10.1016/j.jep.2004.06.013 |
| Popis: | A versatile microplate bioassay for quick and sensitive determination of antibacterial activity was developed for use in screening medicinal plants and identification of their active principles. This assay can be used to determine minimum inhibitory concentrations for small quantities of organic or water-soluble plant extracts. Bioassay-guided fractionation of the stem and leaves of Peperomia galioides using this method found fractions containing grifolin and grifolic acid, which inhibited growth of Staphylococcus aureus and Staphylococcus epidermidis. |
| Databáze: | OpenAIRE |
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