| Autor: |
Jiayuan Guo, Juan Zhao, Ming Gu, Jixiang Hou, Ting Xu, Ying Jiang, Caihong Jiang, Hui Li, Xiaorong Li, Guang Liu, Lanzhen Zhao, Gaowa Jin, Yongzhi Shi, Ting Liu, Zhenhao Li, Zewei Zhang, Quanfu Li |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Nutrition and cancer. |
| ISSN: |
1532-7914 |
| Popis: |
Determine the association of lean body mass (LBM) on the incidence and severity of peripheral neurotoxicity in cancer patients who received nab-paclitaxel alone or combined with cisplatin or carboplatin. This prospective clinical study examined 32 cancer patients classified into a sarcopenia or non-sarcopenia group according to the Asian L3 vertebra skeletal muscle index (L3-SMI) at Ordos Central Hospital (China) from December 2020-2021, to compare the incidence and severity of neurotoxicity and analizing the relationship between nab-paclitaxel dose per kg LBM and neurotoxicity. There were 18 patients (56.25%) in the sarcopenia group and 14 (43.75%) in the non-sarcopenia group. The incidences of peripheral and severe neurotoxicity were higher in the sarcopenia group (both |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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