The Impact of War-Related Stress on Coronary Artery Disease Severity in War Survivors: A SYNTAX Study

Autor: Aseel Saadeh, Hanna K Al-Makhamreh, Hashim Al-Ani, Saif Aldeen AlRyalat, Dana Alkhulaifat, Abdallah Al-Ani, Baraa Mafrachi, Amjad Bani Hani
Rok vydání: 2021
Předmět:
Zdroj: International Journal of Environmental Research and Public Health
Volume 18
Issue 6
International Journal of Environmental Research and Public Health, Vol 18, Iss 3233, p 3233 (2021)
ISSN: 1660-4601
DOI: 10.3390/ijerph18063233
Popis: Background: Due to the strong relationship between stress and heart disease, particularly acute myocardial infarction (MI), this study investigated the complexity of coronary artery disease (CAD) among Syrian refugee patients referred to Jordan University Hospital and its relation to war-related stressors. Methods: This is a retrospective study that utilized the SYNTAX I score in order to evaluate all Syrian refugees that underwent coronary artery catheterization at Jordan University Hospital during the period between May of 2014 and December of 2017. Results: There was a significant association between war-related stressors and high SYNTAX score (SX score), thus indicating a higher complexity of CAD in Syrian war survivors with higher stress scores. The strongest war-related correlation was observed with crossing green-lines, in which Syrian refugee patients who had crossed such lines had significantly higher SYNTAX scores. Regression analysis demonstrated that war stressors were positive predictors of increased SYNTAX scores even when adjusted for conventional CAD risk factors. Surprisingly, none of the CAD risk factors were significantly associated with SYNTAX score. Conclusion: Our findings suggest that exposure to multiple war-related stressors may increase the complexity and severity of CAD in Syrian war survivors. Thus, special attention, efforts, and resources should be allocated to screen for such vulnerable patients in order to provide them with the appropriate healthcare.
Databáze: OpenAIRE