Posttransplant Lymphoproliferative Disorder Involving the Gastrointestinal Tract
| Autor: | Sanam Loghavi, Angad S. Uberoi, Tejas Kirtane, L. Jeffrey Medeiros, Manoop S. Bhutani, Guneesh S. Uberoi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty medicine.medical_treatment epstein–bar virus Hematopoietic stem cell transplantation Malaise 03 medical and health sciences 0302 clinical medicine Cervical lymphadenopathy hemic and lymphatic diseases hematopoietic stem-cell transplantation medicine lcsh:RC799-869 General Environmental Science Gastrointestinal tract medicine.diagnostic_test business.industry Immunosuppression posttransplant lymphoproliferative disorder Endoscopy medicine.anatomical_structure surgical procedures operative 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology lcsh:Diseases of the digestive system. Gastroenterology Bone marrow solid-organ transplantation medicine.symptom Complication business |
| Zdroj: | Journal of Digestive Endoscopy, Vol 11, Iss 04, Pp 293-294 (2020) |
| ISSN: | 0976-5050 0976-5042 |
| Popis: | Posttransplant lymphoproliferative disorder (PTLD) is a rare and life-threatening complication of both solid organ transplantation and hematopoietic stem cell transplantation. In most cases, PTLD develops in Epstein–Barr virus (EBV)-seropositive individuals in the setting of chronic immunosuppression and decreased T-cell surveillance. Clinical manifestations of PTLD may be nonspecific, resembling primary EBV infection (fever, night sweats, malaise, and cervical lymphadenopathy), or it can involve the central nervous system, bone marrow, kidneys, liver, lungs, and gastrointestinal tract. Gastrointestinal symptoms in the posttransplant setting may indicate underlying PTLD, and it is important for physicians to be able to recognize its appearance on endoscopy. |
| Databáze: | OpenAIRE |
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