Detection of Gluten in Duplicate Portions to Determine Gluten Intake of Celiac Disease Patients on A Gluten Free Diet
| Autor: | Maria G. E. G. Bremer, J.H.M. de Vries, H. J. van der Fels-Klerx, M.M. Nijkamp, J. M. Schultink, N. G. E. Smits, J.J.M. Castenmiller |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
0301 basic medicine Food intake Novel Foods & Agrochains Medicine (miscellaneous) WASS Novel Foods & Agroketens Coeliac disease Eating 0302 clinical medicine Medicine Celiac disease BU Toxicology Novel Foods & Agrochains Sensory Science and Eating Behaviour chemistry.chemical_classification Nutrition and Dietetics Dietary intake BU Toxicology Food composition data Middle Aged Diet Records BU Toxicologie Novel Foods & Agroketens Female 030211 gastroenterology & hepatology ELISA Adult Glutens Daily intake BU Toxicologie Bedrijfseconomie digestive system Diet Gluten-Free Young Adult 03 medical and health sciences Animal science BU Authenticity & Bioassays Business Economics Humans VLAG Global Nutrition Wereldvoeding 030109 nutrition & dietetics business.industry nutritional and metabolic diseases Gluten intake medicine.disease Gluten digestive system diseases Sensoriek en eetgedrag BU Authenticiteit & Bioassays chemistry gluten Gluten free gluten free diet Energy Intake business dietary intake Food Analysis |
| Zdroj: | British Journal of Nutrition, 125(9), 1051-1057 British Journal of Nutrition 125 (2021) 9 |
| ISSN: | 0007-1145 |
| Popis: | This study determined the gluten content of foods and meals consumed by coeliac disease (CD) patients who adhere to a gluten-free diet, and to estimate the total daily intake of gluten of these patients. CD patients fulfilling defined inclusion criteria were preselected and approached for participation in the study. Duplicate portions (DP) of foods and mixed dishes were collected from the CD patients for evaluating complete daily food intake during two individual days. Also, for these days, written food records were completed by the participants. From each DP, a laboratory sample was prepared and analysed for its gluten concentration and total daily gluten intake was calculated. Each individual’s total daily intakes of energy and macronutrients were calculated using the Dutch food composition database. In total, twenty-seven CD patients participated, seven males and twenty females, aged between 21 and 64 years. In thirty-two (6 %) of 499 food samples collected in total, more than 3 mg/kg gluten was present. In four of these thirty-two samples, the gluten concentration was above the European legal limit of 20 mg/kg and three of the four samples had a gluten-free label. The maximal gluten intake was 3·3 mg gluten/d. The gluten tolerance for sensitive CD patients (>0·75 mg/d) was exceeded on at least six out of fifty-four study days. To also protect these sensitive CD patients, legal thresholds should be re-evaluated and the detection limit of analytical methods for gluten analysis lowered. |
| Databáze: | OpenAIRE |
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