Macular Hole Formation After Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration

Autor: Arijit Mitra, Chandoshi Mukherjee, Peck Lin Lip, Samer Elsherbiny, N. Ajith Kumar
Rok vydání: 2015
Předmět:
Zdroj: The Open Ophthalmology Journal
ISSN: 1874-3641
DOI: 10.2174/1874364101509010177
Popis: Ranibizumab is a monoclonal antibody fragment that inhibits angiogenesis by inhibiting vascular endothelial growth factor A, used as a treatment for patients with wet aged-related macular degeneration (ARMD). Adverse effects from intravitreal Ranibizumab injections are well recognised. Macular hole formation following Ranibizumab injection is a complication that has been recently reported in few case reports. We present a larger case series of five patients, who developed full thickness macular holes (FTMH) after intravitreal Ranibizumab injections for treatment of wet ARMD that we were aware of between 2009 and 2013.
Databáze: OpenAIRE