Changes in the levels of progesterone, corticosteroids, estrone, estradiol-17 beta, luteinizing hormone, and prolactin in the peripheral plasma of the ewe during late pregnancy and at parturition

Autor: C. G. Winfield, Mildred E. Cerini, J. R. Goding, I. A. Cumming, Joan M. Buckmaster, A. H. Williams, J. M. Obst, Chamley Wa
Rok vydání: 1973
Předmět:
Zdroj: Biology of reproduction. 9(1)
ISSN: 0006-3363
Popis: Serial measurements (up to four times per day) of maternal plasma progesterone, corticosteroids, estrone, estradiol-17�, LH, and prolactin have been made in six sheep, during late pregnancy and at parturition (Day 0). The mean progesterone concentration on Day -10 was 15.5 ng/ml. From Day -4 the level began to decrease and by Day 0, the mean progesterone level was 1.0 ng/ml. The mean concentrations of estrone and estradiol-17p on Day -3 (62.4 and 24.0 pg/ml, respectively) began to rise during the 48 hr preceding parturition, reaching peak values of 228.0 and 141.8 pglml, respectively. The mean corticosteroid level (17.3 ng/ml) rose during the 18 hr preceding parturition, reaching a peak of 38.6 ng/ml. Estrone, estradiol-17�, and corticosteroids returned to low levels within 12 hr after parturition. LH levels remained relatively coastant (2.0-6.0 ng/ml) from -36 h to +30 h but prolactin levels rose sharply from about Day -2. Possible explanations for the absence of an increase in LH secretion, in response to the preparturient rise in estrogens, are discussed.
Databáze: OpenAIRE