Endoscopic scleroligation is a superior new technique for preventing recurrence of esophageal varices
| Autor: | Hiroshi Yoshida, Masahiko Onda, Matsuomi Umehara, Masahito Toba, Kiyohiko Yamashita, Yasuhiro Mamada, Nobuhiko Taniai, Takashi Tajiri |
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| Rok vydání: | 2002 |
| Předmět: |
Male
medicine.medical_specialty Cirrhosis Combination therapy Demographics Esophageal and Gastric Varices Gastroenterology Esophageal varices Injection sclerotherapy Recurrence Internal medicine Sclerotherapy medicine Overall survival Initial treatment Humans Ligation business.industry General Medicine Middle Aged medicine.disease Combined Modality Therapy Sclerosing Solutions Surgery Treatment Outcome Female Esophagoscopy business |
| Zdroj: | Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. 69(2) |
| ISSN: | 1345-4676 |
| Popis: | This study compared a new method, endoscopic scleroligation, intravariceal injection sclerotherapy followed by ligation plus extravariceal injection sclerotherapy, with ligation plus extravariceal injection sclerotherapy. Fifty-nine patients with cirrhosis and esophageal varices were treated by endoscopic scleroligation (ESL group, n = 28) or ligation plus extravariceal injection sclerotherapy (EVL + extraEIS group, n = 31). The demographics and clinical characteristics of the two treatment groups were similar, as was the rate of complete eradication with initial treatment. However, the 1- and 3-year cumulative recurrence rates in the ESL group (3.8% and 22.4%) were very significantly lower than those in the EVL + extraEIS group (48.3% and 81.0%) (p < 0.0001). The overall survival rates in the two groups were similar. In conclusion, endoscopic scleroligation is superior to ligation plus extravariceal injection sclerotherapy in preventing variceal recurrence. The efficacy of intravariceal injection sclerotherapy before ligation is believed to arise from the eradication of feeder vessels. |
| Databáze: | OpenAIRE |
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