A parcellation-based model of the auditory network
Autor: | Michael Y. Bai, Onur Tanglay, Isabella M. Young, R. Dineth Fonseka, Joseph J. Kuiper, Andrew K. Conner, Christen M. O'Neal, Jorge Hormovas, Yueh-Hsin Lin, Vukshitha Dhanaraj, Robert G. Briggs, Michael E. Sughrue |
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Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
Computer science Temporoparietal junction Auditory area Inferior frontal gyrus 03 medical and health sciences Superior temporal gyrus 0302 clinical medicine Neural Pathways Connectome medicine Humans Arcuate fasciculus Auditory Cortex medicine.diagnostic_test Magnetic Resonance Imaging Sensory Systems Diffusion Tensor Imaging 030104 developmental biology medicine.anatomical_structure Frontal lobe Nerve Net Functional magnetic resonance imaging Neuroscience 030217 neurology & neurosurgery Tractography |
Zdroj: | Hearing Research. 396:108078 |
ISSN: | 0378-5955 |
Popis: | Introduction The auditory network plays an important role in interaction with the environment. Multiple cortical areas, such as the inferior frontal gyrus, superior temporal gyrus and adjacent insula have been implicated in this processing. However, understanding of this network's connectivity has been devoid of tractography specificity. Methods Using attention task-based functional magnetic resonance imaging (MRI) studies, an activation likelihood estimation (ALE) of the auditory network was generated. Regions of interest corresponding to the cortical parcellation scheme previously published under the Human Connectome Project were co-registered onto the ALE in the Montreal Neurological Institute coordinate space, and visually assessed for inclusion in the network. Diffusion spectrum MRI-based fiber tractography was performed to determine the structural connections between cortical parcellations comprising the network. Results Fifteen cortical regions were found to be part of the auditory network: areas 44 and 8C, auditory area 1, 4, and 5, frontal operculum area 4, the lateral belt, medial belt and parabelt, parietal area F centromedian, perisylvian language area, retroinsular cortex, supplementary and cingulate eye field and the temporoparietal junction area 1. These regions showed consistent interconnections between adjacent parcellations. The frontal aslant tract was found to connect areas within the frontal lobe, while the arcuate fasciculus was found to connect the frontal and temporal lobe, and subcortical U-fibers were found to connect parcellations within the temporal area. Further studies may refine this model with the ultimate goal of clinical application. |
Databáze: | OpenAIRE |
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