Non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions
| Autor: | Taek Hyeon Kim, Quynh Pham Bao Nguyen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
chiral carboxylic acids
Chiral auxiliary Organic Chemistry asymmetric alkylation 2-imidazolidinone Alkylation Combinatorial chemistry Full Research Paper lcsh:QD241-441 chemistry.chemical_compound Chemistry chiral auxiliaries lcsh:Organic chemistry chemistry Organic chemistry lcsh:Q non-cross-linked polystyrene Polystyrene lcsh:Science Chiral derivatizing agent |
| Zdroj: | Beilstein Journal of Organic Chemistry Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 2113-2119 (2013) |
| ISSN: | 1860-5397 |
| Popis: | Asymmetric alkylation reactions using non-cross-linked polystyrene (NCPS)-supported 2-imidazolidinone chiral auxiliaries were successfully investigated with excellent diastereocontrol (>99% de). The recovery and the recycling of this soluble polymer-supported chiral auxiliary were achieved in order to produce highly optical pure carboxylic acids. |
| Databáze: | OpenAIRE |
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