Nicotine increases cerebellar activity during finger tapping
| Autor: | Narin Wongngamnit, Jason R. Tregellas, Korey P. Wylie, Jody Tanabe, Laura F. Martin |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Cerebellum Nicotine Nicotine patch medicine.medical_treatment lcsh:Medicine Brain mapping Functional Laterality Fingers Reaction Time Medicine Humans lcsh:Science Brain Mapping Multidisciplinary Cross-Over Studies medicine.diagnostic_test business.industry lcsh:R Hemodynamics Brain Crossover study Magnetic Resonance Imaging medicine.anatomical_structure Anesthesia Finger tapping Cerebellar vermis lcsh:Q Female business Functional magnetic resonance imaging Neuroscience Psychomotor Performance medicine.drug Research Article |
| Zdroj: | PLoS ONE PLoS ONE, Vol 8, Iss 12, p e84581 (2013) |
| ISSN: | 1932-6203 |
| Popis: | Nicotine improves performance on several cognitive and sensorimotor tasks. The neuronal mechanisms associated with these changes in performance are, however, largely unknown. Functional magnetic resonance imaging (fMRI) was used to examine the effect of nicotine on neuronal response in nineteen healthy subjects while they performed an auditory-paced finger tapping task. Subjects performed the task, after receiving either a nicotine patch or placebo treatment, in a single blind, crossover design. Compared to placebo, nicotine treatment increased response in the cerebellar vermis. Increased vermal activity, in the absence of changes in other task-related regions suggests specificity in nicotine's effects. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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