Gliadin allergy manifested with chronic urticaria, headache and amenorrhea
| Autor: | Fatmira Xhixha, Entela Hyso, Alkerta Ibranji, Alketa Bakiri, Ervin Ç. Mingomataj, Enkelejda Gjata |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Abdominal pain Malabsorption Urticaria media_common.quotation_subject Autoimmune enteropathy Gastroenterology Article Gliadin Young Adult Bloating Internal medicine medicine Humans Amenorrhea Menstrual cycle media_common biology business.industry Headache food and beverages nutritional and metabolic diseases Gluten intolerance General Medicine medicine.disease digestive system diseases Endocrinology Chronic Disease biology.protein Female medicine.symptom business Food Hypersensitivity |
| Zdroj: | Scopus-Elsevier |
| Popis: | Gluten intolerance is an autoimmune enteropathy caused by heterogeneous mixture of wheat storage proteins. Malabsorption symptoms imply diarrhoea, abdominal pain/bloating and weight loss. This case describes a 22-year-old female subject, who had chronic headache, joint pain, urticaria and long period of amenorrhea. Skin prick tests revealed a sensitisation to α-gliadin, while neurological, gynaecological, endocrine and clinical-laboratory examinations did not justify the above-mentioned symptoms. Gluten-free diet resolved chronic symptoms and re-established the menstrual cycle, whereas a temporary gliadin daily diet re-exacerbated all clinical symptoms. Urticaria occurred 20 min and the chronic headache the next day after exposure to the gliadin-rich diet. In addition, the missing of the expected menstrual bleeding was observed. This case demonstrates that gliadin intake can induce malabsorption and ‘idiopathic’ neuronal or gynaecological symptoms. |
| Databáze: | OpenAIRE |
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