Sensitivity of skin and bronchial mucosa to green algae

Autor: Robert S. Safferman, I.Leonard Bernstein
Rok vydání: 1966
Předmět:
Zdroj: The Journal of allergy. 38(3)
ISSN: 0021-8707
Popis: Six green algal strains were examined for their possible allergenicity to humans. Of 79 atopic patients tested with algal extracts, 47 gave positive skin tests. Non-atopic individuals showed no skin reactivity. Skin-sensitizing antibodies were passively transferred from 6 of 8 patients tested with Chlorella vulgaris. In the same group of patients, precipitating antibodies were not observed. Bronchial mucosal tests, evaluated by changes in the peak expiratory flow rate and by the appearance of clinical wheezing, were performed on 8 patients in whom cutaneous reactivity had been pronounced. Positive responses to acrosolized extracts of Chlorella vulgaris were obtained in 5 of these patients. These results suggest that positive skin tests to green algae are immunologically significant and that these organisms may be etiological agents in human respiratory allergies.
Databáze: OpenAIRE