Prognostic Value of Right Ventricular Longitudinal Peak Systolic Strain in Patients With Pulmonary Hypertension
| Autor: | Martin J. Schalij, Hubert W. Vliegen, Jeroen J. Bax, Marlieke L.A. Haeck, Eduard R. Holman, Victoria Delgado, Nina Ajmone Marsan, Roderick W.C. Scherptong |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Systole Hypertension Pulmonary Speckle tracking echocardiography Kaplan-Meier Estimate Doppler echocardiography Risk Assessment Predictive Value of Tests Risk Factors Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Aged Netherlands Proportional Hazards Models Retrospective Studies Chi-Square Distribution Ejection fraction medicine.diagnostic_test Proportional hazards model business.industry Middle Aged Prognosis medicine.disease Pulmonary hypertension Echocardiography Doppler Predictive value of tests Disease Progression Ventricular Function Right Cardiology lipids (amino acids peptides and proteins) Female Cardiology and Cardiovascular Medicine business Chi-squared distribution |
| Zdroj: | Circulation: Cardiovascular Imaging, 5(5), 628-36 |
| ISSN: | 1942-0080 1941-9651 |
| Popis: | Background— Right ventricular (RV) function is an important prognostic marker in patients with pulmonary hypertension. The present evaluation assessed the prognostic value of RV longitudinal peak systolic strain (LPSS) in patients with pulmonary hypertension. Methods and Results— A total of 150 patients with pulmonary hypertension of different etiologies (mean age, 59±15 years; 37.3% male) were evaluated. RV fractional area change and tricuspid annular plane systolic excursion index were evaluated with 2-dimensional echocardiography. RV LPSS was assessed with speckle-tracking echocardiography. The patient population was categorized according to a RV LPSS value of –19%. Among several clinical and echocardiographic parameters, the significant determinants of all-cause mortality were evaluated. There were no significant differences in age, sex, pulmonary hypertension cause and left ventricular ejection fraction between patients with RV LPSS P =0.003) and lower tricuspid annular plane systolic excursion (16±4 mm versus 18±3 mm; P P =0.02). Conclusions— In patients with pulmonary hypertension, RV LPSS is significantly associated with all-cause mortality. RV LPSS may be a valuable parameter for risk stratification of these patients. Future studies are needed to confirm these results in the pulmonary hypertension subgroups. |
| Databáze: | OpenAIRE |
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