Asymmetric [2,3]-Sigmatropic Rearrangement of Allylic Ammonium Ylides
| Autor: | Peter Somfai, Olaf Panknin, Jan Blid |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
chemistry.chemical_classification
Allylic rearrangement Stereochemistry organic chemicals 2 3-sigmatropic rearrangement Kornblum–DeLaMare rearrangement General Chemistry Sigmatropic reaction Chiral Lewis acid Biochemistry Medicinal chemistry Catalysis Carroll rearrangement chemistry.chemical_compound Colloid and Surface Chemistry Deprotonation chemistry Ylide |
| Zdroj: | Journal of the American Chemical Society. 127:9352-9353 |
| ISSN: | 1520-5126 0002-7863 |
| Popis: | An asymmetric Lewis acid-mediated [2,3]-sigmatropic rearrangement of allylic amines has been developed, affording the corresponding homoallylic amines in good yield and excellent enantioselectivities. The rearrangement proceeds by complexation of the chiral Lewis acid to the amine followed by deprotonation and rearrangement. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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