An overview of concepts and approaches used in estimating the burden of congenital disorders globally
| Autor: | Sowmiya Moorthie, Joan K. Morris, Matthew Darlison, Pierpaolo Mastroiacovo, Bernadette Modell, Hannah Blencowe, Joy E Lawn |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Policy development medicine.medical_specialty Public health business.industry Epidemiology Congenital disorders Public Health Environmental and Occupational Health Psychological intervention 030105 genetics & heredity Demographic data 03 medical and health sciences Premature death Policy Environmental health Medicine Observational study Original Article business Psychiatry Genetics (clinical) Service development |
| Zdroj: | Journal of Community Genetics |
| ISSN: | 1868-6001 1868-310X |
| Popis: | Congenital disorders are an important cause of pregnancy loss, premature death and life-long disability. A range of interventions can greatly reduce their burden, but the absence of local epidemiological data on their prevalence and the impact of interventions impede policy and service development in many countries. In an attempt to overcome these deficiencies, we have developed a tool—The Modell Global Database of Congenital Disorders (MGDb) that combines general biological principles and available observational data with demographic data, to generate estimates of the birth prevalence and effects of interventions on mortality and disability due to congenital disorders. MGDb aims to support policy development by generating country, regional and global epidemiological estimates. Here we provide an overview of the concepts and methodological approach used to develop MGDb. Electronic supplementary material The online version of this article (10.1007/s12687-017-0335-3) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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