Association of HIV infection with age and symptomatic carotid atherosclerotic disease at the time of carotid intervention in the United States
| Autor: | Rodney A. Gabriel, Martin Hoenigl, Brittany N. Burton, Andrew Barleben, Timothy C Lin |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
Carotid Artery Diseases medicine.medical_specialty Time Factors Databases Factual medicine.medical_treatment Human immunodeficiency virus (HIV) HIV Infections Carotid endarterectomy 030204 cardiovascular system & hematology medicine.disease_cause Article 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Carotid artery disease Intervention (counseling) Epidemiology Prevalence medicine Humans cardiovascular diseases Vascular Diseases Aged Retrospective Studies Endarterectomy Endarterectomy Carotid business.industry Angioplasty Age Factors Atherosclerotic disease HIV Stent Middle Aged medicine.disease United States Cross-Sectional Studies cardiovascular system Female Stents Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery |
| Zdroj: | Vascular Medicine. 23:467-475 |
| ISSN: | 1477-0377 1358-863X |
| Popis: | The primary objectives of this work were: (1) to describe trends in HIV prevalence among those undergoing carotid intervention (carotid endarterectomy or carotid artery stenting) in the United States; and (2) to determine if HIV infection is independently associated with symptomatic carotid atherosclerotic disease or age at the time of carotid intervention. In a nationally representative inpatient database from 2004 to 2014, HIV infection was associated with younger age at the time of carotid intervention (59 years [SE 0.2] vs 71 years [SE 0.01], p < 0.001), male sex (83% vs 58%, p < 0.001), black race (21% vs 4%, p < 0.001), and symptomatic carotid atherosclerotic disease (18.8% vs 11.0%, p < 0.001). Among those undergoing carotid intervention, there was a significant increase in the prevalence of HIV from 0.08% in 2004 to 0.17% in 2014 ( p < 0.001). After adjustment for patient demographics, comorbidities and other covariates, HIV infection remained significantly associated with younger age (–8.9 years; 95% CI: –9.7 to −8.1; p < 0.001) at the time of carotid intervention, but HIV infection was not independently associated with symptomatic carotid atherosclerotic disease. |
| Databáze: | OpenAIRE |
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