Autologous connective tissue graft or xenogenic collagen matrix with coronally advanced flaps for coverage of multiple adjacent gingival recession. 36‐month follow‐up of a randomized multicentre trial
| Autor: | Gianpaolo Conforti, Mario Allegri, Jacques Malet, Francesco Cairo, Pierpaolo Cortellini, Filippo Graziani, Heinz Topoll, Ke Deng, Giulio Rasperini, Maurizio S. Tonetti, Daniele Bonaccini, Jan Halben, Adrian Guerrero |
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| Rok vydání: | 2021 |
| Předmět: |
Population
Gingiva Dentistry Connective tissue Matrix (biology) 03 medical and health sciences 0302 clinical medicine Primary outcome root coverage Humans Medicine human 030212 general & internal medicine Tooth Root education Gingival recession randomized controlled clinical trial education.field_of_study business.industry collagen matrix coronally advanced flap gingival recession Collagen Connective Tissue Follow-Up Studies Treatment Outcome Gingival Recession 030206 dentistry Root coverage Confidence interval medicine.anatomical_structure Periodontics medicine.symptom business Gingival margin |
| Zdroj: | Journal of Clinical Periodontology. 48:962-969 |
| ISSN: | 1600-051X 0303-6979 |
| Popis: | Aim To report the 36-month follow-up of a trial comparing the adjunct of a xenogenic collagen matrix (CMX) or connective tissue graft (CTG) to coronally advanced flaps (CAF) for coverage of multiple adjacent recessions. Material and methods 125 subjects (61 CMX) with 307 recessions in 8 centres from the parent trial were followed-up for 36-months. Primary outcome was change in position of the gingival margin. Multilevel analysis used centre, subject, and tooth as levels and baseline parameters as covariates. Results No differences were observed between the randomized and the follow-up population. Average baseline recession was 2.6 ± 1.0 mm. 3-year root coverage was 1.5 ± 1.5 mm for CMX and 2.0 ± 1.0 mm for CTG (difference of 0.32 mm, 95%CI from -0.02 to 0.65 mm). The upper limit of the confidence interval was over the non-inferiority margin of 0.25 mm. No treatment differences in position of the gingival margin were observed between 6- and 36-month follow-up (difference 0.06 mm, 95%CI -0.17 to 0.29 mm). Conclusion CMX was not non-inferior with respect to CTG in multiple adjacent recessions. No differences in stability of root coverage were observed between groups and in changes from 6 to 36 months. Previously reported shorter time to recovery, lower morbidity and more natural appearance of tissue texture and contour observed for CMX in this trial are also relevant in clinical decision making. |
| Databáze: | OpenAIRE |
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