A Solid-phase Radioimmunoassay for the Detection of Antibodies to Treponema pallidum
| Autor: | Trent Dw, Miller Jm, Moody Ee, Donowho Em |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Microbiology (medical)
Radioimmunoassay Fluorescent Antibody Technique Dermatology urologic and male genital diseases Serology Microtiter plate Antigen Pregnancy Solid phase radioimmunoassay Humans Medicine False Positive Reactions Treponema pallidum Treponema biology business.industry Public Health Environmental and Occupational Health medicine.disease biology.organism_classification Antibodies Bacterial Molecular biology Syphilis Serodiagnosis Infectious Diseases Immunoglobulin G biology.protein Female Syphilis Antibody business |
| Zdroj: | Sexually Transmitted Diseases. 6:43-49 |
| ISSN: | 0148-5717 |
| DOI: | 10.1097/00007435-197904000-00001 |
| Popis: | A solid-phase radioimmunoassay (RIA) procedure was developed for the detection of antibodies to Treponema pallidum. The source of antigen used was T. pallidum (Nichols strain), which was specifically bound to the solid phase by use of rabbit antibody to T. pallidum (Nichols strain). The solid-phase system for this RIA test is the well of a microtiter plate. Preliminary data suggest that the RIA procedure is sensitive and specific and might be a useful addition to the research tools and serologic tests used in the study and diagnosis of syphilis. |
| Databáze: | OpenAIRE |
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