Percutaneous cryoablation of chondroblastoma and osteoblastoma in pediatric patients

Autor:	Elena Serrano, Antonio López-Rueda, C. Matthew Hawkins, Daniel Corominas, Fernando Gómez, Enrique Ladera González, Napoleon Macias, Ferran Torner, Anne E. Gill, Emilio J. Inarejos Clemente, Ignasi Barber, Federico Zarco
Rok vydání:	2021
Předmět:	Cryoablation medicine.medical_specialty Percutaneous Radiofrequency ablation medicine.medical_treatment R895-920 Lumbar vertebrae Chondroblastoma 030218 nuclear medicine & medical imaging law.invention Percutaneous thermal ablation 03 medical and health sciences Medical physics. Medical radiology. Nuclear medicine 0302 clinical medicine Osteoblastoma law Medicine Radiology Nuclear Medicine and imaging medicine.diagnostic_test business.industry Interventional radiology medicine.disease medicine.anatomical_structure 030220 oncology & carcinogenesis Thoracic vertebrae Original Article Radiology business
Zdroj:	Insights into Imaging Insights into Imaging, Vol 12, Iss 1, Pp 1-11 (2021)
ISSN:	1869-4101
Popis:	Background To review the safety and efficacy of percutaneous cryoablation for the treatment of chondroblastoma and osteoblastoma in the pediatric and adolescent population. Materials and methods A retrospective review from 2016 to 2020 was performed to evaluate clinical and imaging response to percutaneous cryoablation in 11 symptomatic patients with diagnosis of chondroblastoma and osteoblastoma treated from two pediatric hospitals with at least 12-month follow-up. Technical success (correct needle placement and potential full coverage of the tumor with the planned ablation zone) and clinical success (relief of the symptoms) were evaluated. The primary objective was to alleviate pain related to the lesion(s). Immediate and late complications were recorded. Patients were followed in clinic and with imaging studies such as MRI or CT for a minimum of 6 months. Results A total of 11 patients were included (mean 14 years, age range 9–17; male n = 8). Diagnoses were osteoblastoma (n = 4) and chondroblastoma (n = 7). Locations were proximal humerus (n = 1), femur condyle (n = 1), and proximal femur (n = 1) tibia (n = 3), acetabulum (n = 3), thoracic vertebra (n = 1) and lumbar vertebra (n = 1). Cryoablation was technically successful in all patients. Clinical success (cessation of pain) was achieved in all patients. No signs of recurrence were observed on imaging follow-up in any of the patients. One of the patients developed periprocedural right L2–L3 transient radiculopathy as major immediate complication. Conclusions Percutaneous image-guided cryoablation can be considered potentially safe and effective treatment for chondroblastoma and osteoblastoma in children and adolescents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86067c79c9fef95bcc094ea3b1aa8b1 https://pubmed.ncbi.nlm.nih.gov/34313884 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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