Coronary age, based on coronary calcium measurement, is increased in patients with morbid obesity
| Autor: | Mateusz Hawrył, Waldemar Leszczyński, Marcin Białecki, Adam Lemanowicz |
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| Rok vydání: | 2018 |
| Předmět: |
Original Paper
medicine.medical_specialty business.industry coronary age calcium score Coronary calcium 030204 cardiovascular system & hematology medicine.disease Obesity morbid obesity 030218 nuclear medicine & medical imaging Morbid obesity Coronary artery disease 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Cardiology In patient atherosclerosis Risk factor business Calcium score Obesity paradox |
| Zdroj: | Polish Journal of Radiology |
| ISSN: | 1899-0967 |
| Popis: | Purpose: Obesity is a well-known of risk factor for atherosclerosis. However, recently an "obesity paradox" has been discussed, which is considered as a protective effect of obesity on the development coronary artery disease (CAD). An aim of the study was to investigate the risk of CAD in morbidly obese patients using coronary artery calcium measurement. Material and methods: Fifty-one patients with morbid obesity (BMI ≥ 40 kg/m2) and thirty controls were scanned to determine the amount of coronary artery calcification (CAC), which was expressed as calcium score (CS) and coronary age (CA). The control group consisted of patients scanned for the clinical suspicion of CAD, who did not fulfil the criteria of obesity. Results: Mean BMI of obese patients and controls was 47.3 and 26.5, respectively (p < 0.0001). Arterial hypertension, dyslipidaemia, and smoking were more frequent in the control group than in the obesity group (p < 0.02). The prevalence of CAC was higher in the obesity group (53% vs. 23%, p < 0.01). The groups did not differ regarding CS and CA. However, the difference between coronary age and metrical age was higher in obese patients than in controls (+5.6 vs. -4.8 years, respectively, p < 0.005). Conclusions: Patients with morbid obesity present an increased risk of CAD that is reflected by the difference between their coronary age and metrical age. |
| Databáze: | OpenAIRE |
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