Novel copy number variations of the CHRM3 gene associated with gene expression and growth traits in Chinese Datong yak (Bos grunniens)

Autor: Ding Xue Zhi, Wu Xiaoyun, Min Chu, Ping Yan, Habtamu Abera Goshu, Bao Pengjia
Rok vydání: 2020
Předmět:
Zdroj: Journal of Applied Animal Research, Vol 48, Iss 1, Pp 156-165 (2020)
DOI: 10.6084/m9.figshare.12146055
Popis: A previous study using next-generation sequencing illustrated and confirmed that the cholinergic receptor muscarinic 3 (CHRM3) gene resides within CNVRs of yak populations that overlap with quantitative trait loci (QTL) relating to meat quality and growth, and plays a prominent role in smooth muscle contraction. This study was conducted to determine the distribution of the CNVs of the CHRM3 gene in five Chinese domestic yak breeds and to investigate the influences of the CHRM3 gene on the gene expression and growth traits of the Datong yak. The data were analyzed by ANOVA using SPSS software. Our results revealed that a gain CNV type in the CHRM3 gene is more highly associated (P
Databáze: OpenAIRE