Osteoarthritis? Ochronotic arthritis! A case study and review of the literature
| Autor: | Bai Cheng Chen, De Cheng Shao, Bao Hui Zhao, Qi Zhang |
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| Rok vydání: | 2008 |
| Předmět: |
Male
Pathology medicine.medical_specialty Knee Joint Osteoarthritis Meniscus (anatomy) Alkaptonuria Diagnosis Differential chemistry.chemical_compound Arthroscopy medicine Humans Orthopedics and Sports Medicine Homogentisic acid Ochronosis medicine.diagnostic_test business.industry Cartilage Middle Aged Osteoarthritis Knee medicine.disease medicine.anatomical_structure chemistry Surgery business Rare disease |
| Zdroj: | Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. 17(7) |
| ISSN: | 1433-7347 |
| Popis: | Alkaptonuria is a rare disease in which the body does not have enough of an enzyme called homogentisic acid oxidase. Osteoarthritis is the most common degenerative joint disease. Ochronotic arthritis which resulting from the deposition of oxidized homogentisic acid within the connective tissues of peripheral joints has clinical feature that resembles those of osteoarthritis, but it has a unique manifestation. We reported a case of a patient of ochronotic arthritis, arthroscopic findings showed large areas of darkly pigmented full-thickness cartilage defects in the right knee, the whole meniscal parenchymatous tissue was also darkly pigmented. Histological investigation proved to be ochronosis. |
| Databáze: | OpenAIRE |
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